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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
140
Publications avec texte intégral
Open Access
53 %
Mots clés
Myostatin
Dystrophie myotonique
Myotonic Dystrophy Type 1
Brain dysfunction
GABA
Glucocorticoids
Gene editing
Dystrophin
Expression
Acute coronary syndrome
Muscular dystrophy
In vivo
RNA splicing
Centronuclear myopathy
Genotype phenotype correlation
Hypoxia
PCR
Alternative splicing
Cell penetrating peptide
Humans
CTG repeats
CONGENITAL MYATHENIC SYNDROME
Intermediate filament
BIOLOGIE MOLECULAIRE
Duchenne muscular dystrophy
ARN
Endurance training
CRISPRi
RNA interference
Oligodendrocytes
Myotonic Dystrophy type 1
MBNL
Myotonic dystrophy
Cardiac muscle
Dynamin 2
Transgenic mouse
Fibrosis
Dystrophie Myotonique
Cytoskeleton
Gene Therapy
CRISPR/Cas9
Glucocorticoid-receptor
Trinucleotide Repeat Expansion
CTG repeat instability
Trinucleotide repeat expansion
Glial cells
Maximal force
AAV
Myotonic dystrophy type 1
Diaphragm
Heart
Cell culture model
CTG repeat contractions
Antisense oligonucleotide
Knockout
Gene therapy
DMPK
Mice
RNA biology
Muscle
Glutamate
Myelin
Dilated cardiomyopathy
Antisense oligonucleotides
Transgenic mouse model
Exercice
Aging
DMSXL mice
Autophagy
CMS
Transcriptomics
Heart failure
Acetylcholinesterase knockout mouse
Mouse model
Animals
Brain
Exercise
Thérapie génique
Mouse models
Long read sequencing
DM1
Quantitative microdialysis
Astrocytes
Astrocyte
Oligodendrocyte
Myotonic dystrophy mouse models
KNOCKOUT MICE
GSK3
Skeletal muscle
Central nervous system
Neuron
Therapy
ACETYLCHOLINESTERASE
Male
PacBio
Desmin
Cell model
Motoneuron
Acetylcholinesterase deficiency
Myotonic Dystrophy