Recherche - IRSN - Institut de radioprotection et de sûreté nucléaire

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Radiobiologie des très fortes doses par fraction: connaissances en 2020 et nouvelles modélisations précliniques.

Annaïg Bertho , Morgane dos Santos , Agnes Francois , Fabien Milliat
Radioprotection, 2020, 56 (1), pp.11-24. ⟨10.1051/radiopro/2020072⟩
Article dans une revue hal-03167221v1

Multimodal analysis of small size data to understand the effects of low doses of ionizing radiation on atherosclerosis

Macine Bachir Abdelouahab , Nicolas Rey , Talin Ebrahimian , Celine Gloaguen , Dimitri Kereselidze , et al.
JOBIM2021 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2021, Paris, France. , Proceedings of JOBIM 2021
Poster de conférence irsn-04740064v1
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TGFβ receptor inhibition unleashes interferon-β production by tumor-associated macrophages and enhances radiotherapy efficacy

Pauline Hamon , Marine Gerbé de Thoré , Marion Classe , Nicolas Signolle , Winchygn Liu , et al.
Journal for Immunotherapy of Cancer, 2022, 10 (3), pp.e003519. ⟨10.1136/jitc-2021-003519⟩
Article dans une revue irsn-03980881v1
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Heparan Sulfate Mimetics: A New Way to Optimize Therapeutic Effects of Hydrogel-Embedded Mesenchymal Stromal Cells in Colonic Radiation-Induced Damage

Lara Moussa , Christelle Demarquay , Gildas Réthoré , Mohamed Amine Benadjaoud , Fernando Siñeriz , et al.
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-018-36631-6⟩
Article dans une revue inserm-01985739v1
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Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation

Ian Morilla , Philippe Chan , Fanny Caffin , Ljubica Svilar , Sonia Selbonne , et al.
iScience, 2022, 25, pp.103685. ⟨10.1016/j.isci.2021.103685⟩
Article dans une revue hal-03605168v1

Tumour and normal tissue radiosensitivity

A. Lapierre , S. Gourgou , M. Brengues , L. Quéro , É. Deutsch , et al.
Cancer/Radiothérapie, 2022, 26 (1-2), pp.96-103. ⟨10.1016/j.canrad.2021.11.008⟩
Article dans une revue hal-04522144v1

Assessment of the effects of repeated doses of potassium iodide intake during pregnancy on male and female rat offspring using metabolomics and lipidomics

Clément Rosique , Dalila Lebsir , Philippe Lestaevel , Sheherazade Benatia , Pierre Guigon , et al.
Journal of Toxicology and Environmental Health, Part A: Current Issues, 2019, 82 (10), pp.603-615. ⟨10.1080/15287394.2019.1625474⟩
Article dans une revue hal-02487649v1
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Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome

Alison Accarie , Bruno L’homme , Mohamed Amine Benadjaoud , Sai Kiang Lim , Chandan Guha , et al.
Current Stem Cell Research & Therapy, 2020, 11 (1), pp.1-15. ⟨10.1186/s13287-020-01887-1⟩
Article dans une revue hal-03449961v1
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The Secretome of Human Dental Pulp Stem Cells and Its Components GDF15 and HB-EGF Protect Amyotrophic Lateral Sclerosis Motoneurons against Death

Richard Younes , Youssef Issa , Nadia Jdaa , Batoul Chouaib , Véronique Brugioti , et al.
Biomedicines, 2023, 11 (8), pp.2152. ⟨10.3390/biomedicines11082152⟩
Article dans une revue hal-04498117v1
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Understanding Molecular Mechanisms and Identifying Key Processes in Chronic Radiation Cystitis

Clement Brossard , Anne-Chalotte Lefranc , Jean Marc Simon , Marc Benderitter , Fabien Milliat , et al.
International Journal of Molecular Sciences, 2022, 23 (3), pp.1836. ⟨10.3390/ijms23031836⟩
Article dans une revue hal-03623893v1

Cellular therapy treatment of chronic radiation cystitis in rats

Clement Brossard , Morgane dos Santos , Christelle Demarquay , Valerie Buard , Georges Tarlet , et al.
International Conference on Cell Science and Molecular Biology, CELL SCIENCE-2019, Jul 2019, PARIS, France
Communication dans un congrès hal-03431755v1
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Passage of uranium through human cerebral microvascular endothelial cells:influence of time exposure in mono- and co-culture in vitro models

Celine Gloaguen , Ana F Raimundo , Christelle Elie , Alain Schmitt , Magali Floriani , et al.
International Journal of Radiation Biology, 2020, 96 (12), pp.1597-1607. ⟨10.1080/09553002.2020.1828655⟩
Article dans une revue hal-03080771v2
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Ensembling Unets, sparse representation and low dimensional visualization for rare chromosomal aberration detection and identification in light microscopy images

Antonin Deschemps , Eric Gregoire , Juan S Martinez , Aurelie Vaurijoux , Pascale Fernandez , et al.
2023
Pré-publication, Document de travail hal-04206483v1
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Regenerative medicine for digestive fistulae therapy : benefits, challenges and promises of stem/stromal cells and emergent perspectives via their extracellular vesicles

Anna C. Sebbagh , Boris Rosenbaum , Guillaume Péré , Hadrien Alric , Arthur Berger , et al.
Advanced Drug Delivery Reviews, 2021, 179, pp.113841. ⟨10.1016/j.addr.2021.113841⟩
Article dans une revue hal-03415371v1
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Fabrication and characterization of thin self-rolling film for anti-inflammatory drug delivery

Sidzigui Ouedraogo , Mathilde Grosjean , Isabelle Brigaud , Katia Carneiro , Valeriy Luchnikov , et al.
Colloids and Surfaces B: Biointerfaces, 2024, 241, pp.114039. ⟨10.1016/j.colsurfb.2024.114039⟩
Article dans une revue hal-04633353v1
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Traitement par thérapie cellulaire de la cystite radique chez le rat

Clément Brossard
Biologie cellulaire. Sorbonne Université, 2022. Français. ⟨NNT : 2022SORUS130⟩
Thèse tel-03771184v1
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Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

Kenza Nedara , Camille Reinhardt , Emilie Lebraud , Giuseppe Arena , Céline Gracia , et al.
Frontiers in Oncology, 2022, 12, pp.958155. ⟨10.3389/fonc.2022.958155⟩
Article dans une revue hal-03866235v1

Stromal vascular fraction for the treatment of the radiation-induced gastrointestinal syndrome

Christine Linard , Claire Squiban , Christelle Demarquay , Bruno L'Homme , Noelle Mathieu , et al.
IFATS 2019 - 17th annual international conference of International Federation for Adipose Therapeutics and Science, Dec 2019, Marseille, France
Communication dans un congrès irsn-03981162v1
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CHRONIC INFLAMMATION AND RADIATIONINDUCED CYSTITIS: MOLECULAR BACKGROUND AND THERAPEUTIC PERSPECTIVES.

Carole Helissey , Sophie Cavallero , Clement Brossard , Marie Dusaud , Cyrus Chargari , et al.
Cells, 2020, 10 (1), pp.21. ⟨10.3390/cells10010021⟩
Article dans une revue hal-03152877v1

Metabolomics evaluation of repeated administration of potassium iodide on adult male rats

Clément Rosique , Dalila Lebsir , Sheherazade Benatia , Pierre Guigon , François Caire-Maurisier , et al.
Archives of Toxicology, 2020, 94 (3), pp.803-812. ⟨10.1007/s00204-020-02666-w⟩
Article dans une revue hal-03159938v1
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Repeated potassium iodide exposure during pregnancy impairs progeny’s brain development

D. Lebsir , J. Guemri , D. Kereselidze , S. Grison , M. Benderitter , et al.
Neuroscience, 2019, 406, pp.606-616. ⟨10.1016/j.neuroscience.2019.02.016⟩
Article dans une revue hal-02524208v1
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Etude de l’effet d’un traitement par Faecalibacterium prausnitzii dans un modèle pré-clinique d’atteintes colorectales radio-induites

Alexia Lapiere
Médecine humaine et pathologie. Sorbonne Université, 2020. Français. ⟨NNT : 2020SORUS147⟩
Thèse tel-03254201v1
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Evaluation of the Effectiveness of Mesenchymal Stem Cells of the Placenta and Their Conditioned Medium in Local Radiation Injuries

Vitaliy Brunchukov , Tatiana Astrelina , Daria Usupzhanova , Anna Rastorgueva , Irina Kobzeva , et al.
Cells, 2020, 9 (12), pp.2558. ⟨10.3390/cells9122558⟩
Article dans une revue hal-03152876v1
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The stromal vascular fraction mitigates radiation-induced gastrointestinal syndrome in mice

Lydia Bensemmane , Claire Squiban , Christelle Demarquay , Noëlle Mathieu , Marc Benderitter , et al.
Current Stem Cell Research & Therapy, 2021, 12, pp.309. ⟨10.1186/s13287-021-02373-y⟩
Article dans une revue hal-03448967v1
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Cell to Cell Variability of Radiation-Induced Foci: Relation between Observed Damage and Energy Deposition

Gaetan Gruel , Carmen Villagrasa , Pascale Voisin , Isabelle Clairand , Marc Benderitter , et al.
PLoS ONE, 2016, 11 (1), ⟨10.1371/journal.pone.0145786⟩
Article dans une revue hal-02345047v1
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Systemically delivered adipose stromal vascular fraction mitigates radiation-induced gastrointestinal syndrome by immunomodulating the inflammatory response through a CD11b+ cell-dependent mechanism

Lydia Bensemmane , Fabien Milliat , Xavier Treton , Christine Linard
Stem Cell Research and Therapy, 2023, 14 (1), pp.325. ⟨10.1186/s13287-023-03562-7⟩
Article dans une revue irsn-04282439v1
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A systems biology approach to propose a new mechanism of regulation of repetitive prophylaxis of stable iodide on sodium/iodide symporter (NIS).

David Cohen , Dalila Lebsir , Marc Benderitter , Maamar Souidi
Biochimie, 2019, 162, pp.208-215. ⟨10.1016/j.biochi.2019.04.024⟩
Article dans une revue hal-02457221v1
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Glomerular endothelial cell senescence drives age‐related kidney disease through PAI‐1

Camille Cohen , Océane Le Goff , Frédéric Soysouvanh , Florence Vasseur , Marine Tanou , et al.
EMBO Molecular Medicine, 2021, 13 (11), ⟨10.15252/emmm.202114146⟩
Article dans une revue irsn-03980928v1
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Mesenchymal stem cells limit vascular and epithelial damage and restore the impermeability of the urothelium in chronic radiation cystitis

Clément Brossard , Anne-Laure Pouliet , Anne-Charlotte Lefranc , Mohamedamine Benadjaoud , Morgane dos Santos , et al.
Stem Cell Research and Therapy, 2023, 14 (1), pp.5. ⟨10.1186/s13287-022-03230-2⟩
Article dans une revue irsn-03980856v1
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Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering

M. Heinonen , Fabien Milliat , Mohamed‐amine Benadjaoud , Agnes Francois , Valerie Buard , et al.
PLoS ONE, 2018, 13 (10), pp.e0204960. ⟨10.1371/journal.pone.0204960⟩
Article dans une revue hal-02881802v1